The ODX Blog

Inflammation: A focus on cytokines Part 1 Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Cytokines are basically messengers that facilitate immune function and take part in pro-inflammatory, anti-inflammatory, and allergic responses. [1]

Inflammation and aging combine to create “inflammaging.” Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Aging has been associated with a perpetual inflammatory cascade that involves IL-1alpha, IL-6, and NF-kappa B. Inflammaging refers to chronic low-grade systemic inflammation associated with aging but not caused by an infectious agent.

Inflammation the fire inside: Overview Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Inflammation refers to signs, symptoms, and cellular actions that occur in a complex response to infection, injury, trauma, overuse, toxins, or radiation exposure. Technically inflammation is a is a defense mechanism.[1]

Optimal - The Podcast: Episode 5: The HOMA2 Calculator in Clinical Practice - an Interview with Dr. Brad Rachman Dr. Dicken Weatherby This is a must-watch interview for anyone assessing and treating blood sugar dysregulation in their clinic. Dr. Brad Rachman of the Rachman Clinic shares his 10+ years of experience of using the HOMA2 calculator in his clinical practice. A must-have tool to uncover early stage Insulin Resistance and other dysfunctions of blood sugar regulation. This tool has been built into the ODX Software application.

How to correct B12 deficiency, choosing the right type of B12, dosage, food sources, etc. Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Is the current RDA enough? The RDA Dietary Reference Intake (DRI) for vitamin B12 is 2.4 ug/day for non-pregnant, non-lactating adults.[1]

Biomarkers and how we can assess for B12 deficiency Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN A full clinical assessment of B12 status includes review of signs and symptoms as well as extended blood chemistry analysis. Assessment of B12 status can be complex because: [1]

The road to B12 deficiency and what happens when we get there… Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Elderly status, strict vegetarianism, and lack of intrinsic factor have been traditionally recognized as the main causes of B12 deficiency.[1]

Vitamin B12 Biochemistry and Physiology Dicken Weatherby, N.D. and Beth Ellen DiLuglio, MS, RDN, LDN Vitamin B12, a cobalt-containing compound known as cobalamin, is synthesized by bacteria yet essential to humans. The term cobalamin is a generic term for corrinoids (containing a corrin nucleus).[1]

Subscribe to Optimal on these popular channels Optimal - The Podcast: Episode 4: All About Vitamin B12 and Vitamin B12 Deficiency Dr. Dicken Weatherby & Beth Ellen DiLuglio, MS, RDN, LDN Vitamin B12 or cobalamin is an essential micronutrient required for proper red blood cell production, DNA formation, nerve function, and metabolism.

We are excited to announce that we have added over 35 new biomarkers into the Optimal DX software application. Please watch this short video explaining the biomarkers and how to use the Lab Templates to feature these in your Functional Health Reports: